The Science Museum is located on a central plot of the Cultural village island and is part of the larger mixed development plan. The building is to be one of a series of institutional projects located along the Dubai Creek water edge.

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This man-made island is well connected to the rest of the development plot via a vehicular ring road and four pedestrian bridges.

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Ring road apex is approximately + 6m above ground level due to the need to maintain water transport and pedestrian promenade accessibility.

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The tallest part of the building (the Imax sphere ) is 33m above water level or 32m above ground level.